cenobamate will increase the amount or impact of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep an eye on Intently. Look at a dose reduction of CYP2C19 substrates, as clinically correct, when utilized concomitantly with cenobamate.diazepam will increase amounts of lomitapide by impacting hepatic/intestinal enzyme CYP3A